Sayce opens with the geography of the Tigris and Euphrates, noting that the river name Tigris derives from the Persian word for 'arrow,' a detail that signals the blend of linguistic and historical analysis throughout the primer. The work is structured as a series of compact chapters covering the country, decipherment, history, religion, literature, and social life, each drawing on cuneiform sources and archaeological findings available in the late nineteenth century.

The author, a professor of Assyriology at Oxford, writes with an authoritative yet accessible tone, frequently citing specific monuments, tablets, and inscriptions. The primer does not assume prior knowledge, but it expects attentive reading, as Sayce moves briskly from Sumerian origins to Assyrian imperial campaigns, always grounding his statements in textual evidence.

Geography and Language as Foundations

Sayce devotes the first chapter to the physical setting and linguistic heritage of Babylonia and Assyria. He explains that the Sumerian name for the Tigris, Idikna, was adapted by Semitic speakers into Idiklat, later shortened to Diklat and then assimilated to Persian Tigra ('arrow'), which became the classical Tigris. This etymological chain illustrates how the region's languages—Sumerian, Semitic, Persian—interacted over millennia.

The chapter also describes natural products like asphalt and naphtha, the canal system, and the distinctive architecture of the cities. Sayce emphasizes that the character of the Babylonians and Assyrians was shaped by their environment, yet he avoids deterministic claims, instead presenting observations drawn from inscriptions and archaeological remains. The inclusion of the Chaldaeans and Kassi as distinct groups within the population shows his attention to ethnic and linguistic diversity.

Decipherment and the Recovery of the Past

In the second chapter, Sayce recounts the discovery of the sites of Babylon and Nineveh and the subsequent decipherment of cuneiform inscriptions. He notes that the decipherment was tested against known historical events, lending credibility to the emerging field. The chapter introduces Sumerian as a non-Semitic language and mentions Vannic and other languages deciphered through the cuneiform syllabary.

Sayce traces the origin of the cuneiform script to a pictographic system that was gradually simplified. He does not overstate the certainty of early readings; instead, he presents the process as an ongoing scholarly endeavor. The chapter serves as a methodological grounding for the historical narratives that follow, reminding readers that our knowledge of Assyria and Babylonia depends on the painstaking work of philologists and archaeologists.

Empire and Expansion: From Tiglath-pileser I to Assur-bani-pal

The historical chapter covers the rise of Assyria, the first and second Assyrian empires, and the later Babylonian empire. Sayce highlights key rulers: Tiglath-pileser I, who expanded Assyrian power; Esar-haddon, who conquered Egypt after a remarkable march through Arabia; and Assur-bani-pal, the 'Grand Monarque' who patronized literature but lacked warlike instincts. The account of Esar-haddon's campaign includes specific details: fifteen days from the frontier to Memphis, the wounding of Tirhakah, and the fall of Memphis in June 670 BCE.

Sayce also describes the revolt of Saul-suma-yukin and the role of Gyges of Lydia. The narrative is dense with names and dates, but it consistently ties events to textual sources, such as the prophet Nahum's allusion to the destruction of Thebes. The chapter ends with the decay of Babylon under Cyrus, noting the figure of Belshazzar from the Book of Daniel.

Sayce's primer is best read as a series of interconnected essays rather than a continuous narrative. Readers may find it useful to consult the appendices—which list kings, deities, and synchronisms with biblical history—while moving through the chapters. The work reflects the state of Assyriology in 1894, and later discoveries have refined many details, but the primer remains valuable for its clear exposition of foundational evidence and its demonstration of how philology, archaeology, and history converge.